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Study: Out of the 23 patients with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), 43% had a bacterial infection (majority involving strep), but 57% reportedly had a viral infection.

24.08.201910:28 Julie From

Study 2019

All 23 patients in this small study had a confirmed or suspected viral or bacterial infection around the time of symptom onset.
Patients included 10 girls and 13 boys, ages 4-14.
Study found:
  • Average age of PANS onset was 8.5 years;
  • 48% had a family history (1rst degree relative) with developmental or neuropsychiatric disorders;
  • 48% had a family history (1rst degree relative) with autoimmune or inflammatory diseases;
  • 74% of the patients had been diagnosed previously with a developmental disorder or had associated symptoms.
  • 63% of the children (N=19) who received antibiotic treatment showed improvement in symptoms, according to parental reports.
The study’s authors concluded that PANS patients suffer from severe and an acute-onset of “complex neuropsychiatric symptoms which present with a relapsing-remitting course.”