Study: Out of the 23 patients with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), 43% had a bacterial infection (majority involving strep), but 57% reportedly had a viral infection.
STUDY 2019
All 23 patients in this small study had a confirmed or suspected viral or bacterial infection around the time of symptom onset.Patients included 10 girls and 13 boys, ages 4-14.Study found:
Average age of PANS onset was 8.5 years;
48% had a family history (1rst degree relative) with developmental or neuropsychiatric disorders;
48% had a family history (1rst degree relative) with autoimmune or inflammatory diseases;
74% of the patients had been diagnosed previously with a developmental disorder or had associated symptoms.
63% of the children (N=19) who received antibiotic treatment showed improvement in symptoms, according to parental reports.
The study’s authors concluded that PANS patients suffer from severe and an acute-onset of “complex neuropsychiatric symptoms which present with a relapsing-remitting course.”
